製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to ZNF364
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide:

    C-DQDNRANERGHQTH

    , corresponding to internal sequence amino acids 97-110 of Human ZNF364

  • ポジティブ・コントロール
    • HEPG2 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab52016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    Peptide ELISA: Antibody detection limit dilution 1:32,000.
    WB: Use at a concentration of 0.3 - 1.0 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.
    • 組織特異性
      Expressed at extremely low levels in normal breast, prostate, lung, colon. Higher levels of expression are detected in heart, skeletal muscle, testis as well as in breast and prostate cancer cells.
    • パスウェイ
      Protein modification; protein ubiquitination.
    • 配列類似性
      Contains 1 RING-type zinc finger.
    • 翻訳後修飾
      RING-type zinc finger-dependent and E2-dependent autoubiquitination.
    • 細胞内局在
      Cytoplasm > cytosol. The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BCA2 antibody
      • Breast cancer associated gene 2 antibody
      • CL469780 antibody
      • E3 ubiquitin-protein ligase RNF115 antibody
      • Rabring 7 antibody
      • RING finger protein 115 antibody
      • RN115_HUMAN antibody
      • RNF115 antibody
      • Zinc finger protein 364 antibody
      see all

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    プロトコール

    参考文献

    ab52016 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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