製品の概要

  • 製品名
    Anti-ZNF312B antibody
  • 製品の詳細
    Rabbit polyclonal to ZNF312B
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Rabbit
  • 免疫原

    A synthetic peptide corresponding to a region corresponding within C terminal amino acids 397-446 (

    CPTCGKGFCRNFDLKKHVRKLHDSSLGLARTPAGEPGTEPPPPLPQQPPM

    ) of Human ZNF312B (NP_001019784)

  • ポジティブ・コントロール
    • HeLa cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab81251 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors.
  • 組織特異性
    Expressed in brain. Little or no expression in other tissues. Overexpresssed specifically in gastic cancers. A 2-to 20-fold increase is found in over 50% of gastric cancer tissues.
  • 配列類似性
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 6 C2H2-type zinc fingers.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FEZ antibody
    • FEZ family zinc finger 1 antibody
    • Fez family zinc finger protein 1 antibody
    • fez like antibody
    • fezf1 antibody
    • FEZF1_HUMAN antibody
    • Zinc finger protein 312 like antibody
    • Zinc finger protein 312B antibody
    see all

画像

  • Anti-ZNF312B antibody (ab81251) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 52 kDa
    Observed band size : 52 kDa
    Additional bands at : 80 kDa,>90 kDa. We are unsure as to the identity of these extra bands.
  • ab81251 at 5 µg/ml staining ZNF312B in Human cerebellum by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
  • ab81251 at 5 µg/ml staining ZNF312B in Human pancreas by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
  • ab81251 at 5 µg/ml staining ZNF312B in Human placenta by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

参考文献

This product has been referenced in:

See 1 Publication for this product

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