製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ZMYM2
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 1327 and 1377 of Human ZMYM2 (NP_003444.1).

  • ポジティブ・コントロール
    • Human Controls: Anaplastic Thyroid Carcinoma, Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma Mouse Controls: Teratoma

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab114996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections

ターゲット情報

  • 機能
    May function as a transcription factor.
  • 関連疾患
    Note=A chromosomal aberration involving ZMYM2 may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Translocation t(8;13)(p11;q12) with FGFR1. SCLL usually presents as lymphoblastic lymphoma in association with a myeloproliferative disorder, often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow.
  • 配列類似性
    Contains 9 MYM-type zinc fingers.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 製品の状態
    There are 2 isoforms produced by alternative splicing.
  • 別名
    • FIM antibody
    • Fused in myeloproliferative disorders protein antibody
    • MYM antibody
    • RAMP antibody
    • Rearranged in an atypical myeloproliferative disorder antibody
    • Rearranged in atypical myeloproliferative disorder protein antibody
    • SCLL antibody
    • ZFP 198 antibody
    • Zinc finger MYM type containing 2 antibody
    • Zinc finger MYM type protein 2 antibody
    • Zinc finger MYM-type protein 2 antibody
    • Zinc finger protein 198 antibody
    • Zinc finger protein198 antibody
    • zinc finger, MYM-type 2 antibody
    • ZMYM 2 antibody
    • ZMYM2 antibody
    • ZMYM2_HUMAN antibody
    • ZNF 198 antibody
    • ZNF198 antibody
    see all

画像

  • ab114996, at a 1/250 dilution, staining ZMYM2 in formalin fixed paraffin embedded Human small cell lung cancer by Immunohistochemistry. Detected using DAB staining.
  • ab114996, at a 1/250 dilution, staining ZMYM2 in formalin fixed paraffin embedded Human breast carcinoma by Immunohistochemistry. Detected using DAB staining.
  • ab114996, at a 1/250 dilution, staining ZMYM2 in formalin fixed paraffin embedded Mouse teratoma by Immunohistochemistry. Detected using DAB staining.

プロトコール

参考文献

ab114996 has not yet been referenced specifically in any publications.

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