製品の概要

  • 製品名ZM 241385
  • 製品の詳細
    Potent, selective A2A antagonist
  • 生理活性の詳細Potent A2 adenosine receptor antagonist, with approx 50-fold selectivity for A2A receptors. (Ki values are <1 nM, 50 nM, 255 nM and >10 μM at human cloned A2A, A2B, A1 and A3 receptors, respectively). Orally active in vivo.
  • 精製度> 99%

製品の特性

    ZM 241385 (ab120218) 使用論文

    This product has been referenced in:
    • Orru M  et al. Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists. PLoS One 6:e16088 (2011). Read more (PubMed: 21264319) »
    • Ongini E  et al. Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 359:7-10 (1999). Read more (PubMed: 9933143) »
    • Keddie JR  et al. In vivo characterisation of ZM 241385, a selective adenosine A2A receptor antagonist. Eur J Pharmacol 301:107-13 (1996). Read more (PubMed: 8773453) »
    • Poucher SM  et al. The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2a selective adenosine receptor antagonist. Br J Pharmacol 115:1096-102 (1995). Read more (PubMed: 7582508) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120218.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"