製品の概要

  • 製品名
    Anti-ZFYVE28 antibody
  • 製品の詳細
    Rabbit polyclonal to ZFYVE28
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 611-642 of Human ZFYVE28 (NP_001166130.1, NP_001166131.1, NP_066023.2, NP_001166127.1, NP_001166129.1).

  • ポジティブ・コントロール
    • Mouse heart tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 96 kDa.

ターゲット情報

  • 機能
    Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.
  • 配列類似性
    Belongs to the lst-2 family.
    Contains 1 FYVE-type zinc finger.
  • ドメイン
    The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not monoubiquitinated at Lys-87.
  • 翻訳後修飾
    Monoubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes.
  • 細胞内局在
    Cytoplasm > cytosol. Early endosome membrane. Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated.
  • Information by UniProt
  • 参照データベース
  • 別名
    • hLst2 antibody
    • Lateral signaling target protein 2 homolog antibody
    • LST2 antibody
    • LST2_HUMAN antibody
    • LYST2 antibody
    • MGC43699 antibody
    • MGC61592 antibody
    • zfyve28 antibody
    • Zinc finger FYVE domain containing 28 antibody
    • Zinc finger FYVE domain-containing protein 28 antibody
    see all

画像

  • Anti-ZFYVE28 antibody (ab107913) at 1/100 dilution + Mouse heart tissue lysate at 35 µg

    Predicted band size: 96 kDa

プロトコール

参考文献

ab107913 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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