ZFYVE1 contains two zinc-binding FYVE domains in tandem. The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. There are two named isoforms of ZFYVE1.
Golgi apparatus, Golgi stack.
Note: Resides predominantly in the cisternal stacks of the Golgi.