Anti-ZDHHC9 抗体 (ab74504)
Key features and details
- Rabbit polyclonal to ZDHHC9
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ZDHHC9 antibody
ZDHHC9 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ZDHHC9 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide derived from C-terminal region of human ZDHHC9.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab74504の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/1000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
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IHC-P |
1/50 - 1/100.
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特記事項 |
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WB
1/500 - 1/1000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa). |
IHC-P
1/50 - 1/100. |
ターゲット情報
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機能
The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. -
組織特異性
Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes. -
関連疾患
Defects in ZDHHC9 are the cause of mental retardation syndromic X-linked ZDHHC9-related (MRXSZ) [MIM:300799]. A disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Some patients have marfanoid habitus as an additional feature. -
配列類似性
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Contains 1 DHHC-type zinc finger. -
ドメイン
The DHHC domain is required for palmitoyltransferase activity. -
細胞内局在
Endoplasmic reticulum membrane. Golgi apparatus membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 51114 Human
- Entrez Gene: 208884 Mouse
- Entrez Gene: 302808 Rat
- Omim: 300646 Human
- SwissProt: Q9Y397 Human
- SwissProt: P59268 Mouse
- Unigene: 193566 Human
- Unigene: 207367 Mouse
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別名
- Antigen MMSA 1 antibody
- Asp His His Cys domain containing protein 9 antibody
- CGI89 antibody
see all
画像
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All lanes : Anti-ZDHHC9 antibody (ab74504) at 1/500 dilution
Lane 1 : extracts from COLO cells
Lane 2 : extracts from COLO cells with immunising peptide at 10 µg
Lysates/proteins at 30 µg per lane.
Predicted band size: 41 kDa
Observed band size: 41 kDa
Additional bands at: 26 kDa, 34 kDa, 48 kDa. We are unsure as to the identity of these extra bands. -
Immunohistochemistry analysis of paraffin-embedded human brain tissue using 1/50 ab74504. Left: untreated sample. Right: sample treated with immunising peptide.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab74504 は 3 報の論文で使用されています。
- Chong X et al. ZDHHC9 promotes colon tumor growth by inhibiting effector T cells. Oncol Lett 25:5 (2023). PubMed: 36419754
- Yao H et al. A peptidic inhibitor for PD-1 palmitoylation targets its expression and functions. RSC Chem Biol 2:192-205 (2021). PubMed: 34458782
- Cambronne XA et al. Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach. Proc Natl Acad Sci U S A 109:20473-8 (2012). WB . PubMed: 23184980