製品の概要

  • 製品名Anti-ZCCHV antibody
    ZCCHV 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ZCCHV
  • 特異性ab105357 is predicted to not crossreact with other ZAP members. Four isoforms of ZCCHV are known to exist.
  • アプリケーション適用あり: ICC/IF, WB, ICCmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A 14 amino acid synthetic peptide near the C terminus of Human ZCCHV (NP_078901).

  • ポジティブ・コントロール
    • WB: HeLa cell lysate ICC: HeLa cells

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab105357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 101 kDa.
ICC Use a concentration of 20 µg/ml.

ターゲット情報

  • 機能Induces an innate immunity to viral infections by preventing the accumulation of viral RNAs in the cytoplasm. Seems to recruit the RNA processing exosome to degrade the target RNAs. Inhibits alphavirus and filovirus replication.
  • 配列類似性Contains 4 C3H1-type zinc fingers.
    Contains 1 PARP catalytic domain.
    Contains 1 WWE domain.
  • ドメインThe second and fourth zinc fingers are involved in binding to specific viral RNAs.
  • 細胞内局在Cytoplasm. Nucleus. Localizes in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADP ribosyltransferase diphtheria toxin like 13 antibody
    • ARTD13 antibody
    • FLB6421 antibody
    • PARP13 antibody
    • ZAP antibody
    • ZC3H2 antibody
    • ZC3HAV 1 antibody
    • Zc3hav1 antibody
    • ZC3HDC 2 antibody
    • ZC3HDC2 antibody
    • ZCCHV_HUMAN antibody
    • Zinc finger antiviral protein antibody
    • Zinc finger CCCH domain containing protein 2 antibody
    • Zinc finger CCCH domain-containing antiviral protein 1 antibody
    • Zinc finger CCCH domain-containing protein 2 antibody
    • Zinc finger CCCH type antiviral 1 antibody
    • Zinc finger CCCH type antiviral protein 1 antibody
    • Zinc finger CCCH-type antiviral protein 1 antibody
    see all

Anti-ZCCHV antibody 画像

  • Anti-ZCCHV antibody (ab105357) at 1 µg/ml + HeLa cell lysate at 15 µg

    Predicted band size : 101 kDa
  • Immunocytochemical analysis of ZCCHV in HeLa cells stained with ab105357 at 20 µg/ml.
  • Immunofluorescence of ZC3HAV1 in Hela cells using ab105357 at 20 ug/ml.

Anti-ZCCHV antibody (ab105357) 使用論文

This product has been referenced in:
  • Lee H  et al. Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus. Proc Natl Acad Sci U S A 110:12379-84 (2013). Read more (PubMed: 23836649) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"