製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ZBTB7A
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide corresponding to a region between residue 525 and the C terminus (residue 584) of Human ZBTB7A (NP_056982.1).

  • ポジティブ・コントロール
    • Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Lung Adenocarcinoma, Non Small Cell Lung Cancer, Ovarian Carcinoma, Placenta, Prostate Carcinoma, Stomach Adenocarcinoma.
  • 特記事項
    The concentration of IgG is less than or equal to 1 mg/ml.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium azide
    Constituents: 99% Tris buffered saline, 0.1% BSA
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab114074 was affinity purified using an epitope specific to ZBTB7A immobilized on a solid support.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab114074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. Antigen retrieval is recommended. Likely to work with frozen sections In some cases, the antibody may be diluted further than indicated.

ターゲット情報

  • 機能
    Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
  • 組織特異性
    Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
  • 配列類似性
    Contains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp547O146 antibody
    • Factor binding IST protein 1 antibody
    • Factor that binds to inducer of short transcripts protein 1 antibody
    • FBI-1 antibody
    • FBI1 antibody
    • HIV-1 1st-binding protein 1 antibody
    • HIV-1 inducer of short transcripts binding protein antibody
    • HIV-1 inducer of short transcripts-binding factor 1 antibody
    • Leukemia/lymphoma-related factor antibody
    • LRF antibody
    • lymphoma related factor antibody
    • MGC99631 antibody
    • POK erythroid myeloid ontogenic factor antibody
    • Pokemon antibody
    • POZ and Krueppel erythroid myeloid ontogenic factor antibody
    • TIP21 antibody
    • TTF-I-interacting peptide 21 antibody
    • ZBT7A_HUMAN antibody
    • ZBTB7 antibody
    • ZBTB7A antibody
    • Zinc finger and BTB domain containing 7A antibody
    • zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein antibody
    • Zinc finger and BTB domain-containing protein 7A antibody
    • Zinc finger protein 857A antibody
    • Zinc finger- and BTB domain-containing protein 7 antibody
    • ZNF857A antibody
    see all

画像

  • ab114074 at 1/250 dilution staining ZBTB7A in Formalin-Fixed, Paraffin-Embedded Human Breast carcinoma tissue by Immunohistochemistry. Detection utilised DAB.
  • ab114074 at 1/250 dilution staining ZBTB7A in Formalin-Fixed, Paraffin-Embedded Human Colon carcinoma tissue by Immunohistochemistry. Detection utilised DAB.

プロトコール

参考文献

ab114074 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for contacting Abcam regarding ab114074.


This antibody has not been tested in WB, therefore we do not know if or how well it will work in this application. Generally speaking, I would start by testing several dilutions, rangin...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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