製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ZBTB7A
  • 特異性
    At least two isoforms of ZBTB7A are known to exist; ab106592 will recognize both isoforms. Predicted to not cross-react with other ZBTB protein family members.
  • アプリケーション
    適用あり: ICC/IF, WB, ICC, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A 16 amino acid synthetic peptide from near the N-terminus of Human ZBTB7A (AAH84568).

  • ポジティブ・コントロール
    • Human ovary tissue lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab106592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 61 kDa.
ICC Use a concentration of 2.5 µg/ml.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
  • 組織特異性
    Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
  • 配列類似性
    Contains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp547O146 antibody
    • Factor binding IST protein 1 antibody
    • Factor that binds to inducer of short transcripts protein 1 antibody
    • FBI-1 antibody
    • FBI1 antibody
    • HIV-1 1st-binding protein 1 antibody
    • HIV-1 inducer of short transcripts binding protein antibody
    • HIV-1 inducer of short transcripts-binding factor 1 antibody
    • Leukemia/lymphoma-related factor antibody
    • LRF antibody
    • lymphoma related factor antibody
    • MGC99631 antibody
    • POK erythroid myeloid ontogenic factor antibody
    • Pokemon antibody
    • POZ and Krueppel erythroid myeloid ontogenic factor antibody
    • TIP21 antibody
    • TTF-I-interacting peptide 21 antibody
    • ZBT7A_HUMAN antibody
    • ZBTB7 antibody
    • ZBTB7A antibody
    • Zinc finger and BTB domain containing 7A antibody
    • zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein antibody
    • Zinc finger and BTB domain-containing protein 7A antibody
    • Zinc finger protein 857A antibody
    • Zinc finger- and BTB domain-containing protein 7 antibody
    • ZNF857A antibody
    see all

画像

  • Immunofluorescence of ZBTB7A in Human ovary tissue with ab106592 at 20 ug/mL.
  • Lane 1 : Anti-ZBTB7A antibody (ab106592) at 1 µg/ml
    Lane 2 : Anti-ZBTB7A antibody (ab106592) at 2 µg/ml

    Lane 1 : Human ovary tissue lysate
    Lane 2 : Human ovary tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 61 kDa
  • Immunohistochemistry of ZBTB7A in Human ovary tissue with ab106592 at 2.5 µg/ml.

参考文献

ab106592 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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