製品の概要

  • 製品名Anti-ZAN antibody
    ZAN 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to ZAN
  • アプリケーション適用あり: WB, ELISA, Sandwich ELISAmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 19-114 of Human ZAN with a proprietary tag (NP_003377).

  • ポジティブ・コントロール
    • Recombinant Human ZAN Protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab118116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 306 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
  • 組織特異性In testis, primarily in haploid spermatids.
  • 配列類似性Contains 1 EGF-like domain.
    Contains 3 MAM domains.
    Contains 4 TIL (trypsin inhibitory-like) domains.
    Contains 5 VWFC domains.
    Contains 4 VWFD domains.
  • ドメインThe MAM domains probably mediate sperm adhesion to the zona pellucida.
    During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus.
    The VWFD domain 2 may mediate covalent oligomerization.
  • 細胞内局在Cell membrane. Exclusively on the apical region of the sperm head.
  • Information by UniProt
  • 参照データベース
  • 別名
    • OTTHUMP00000211358 antibody
    • OTTHUMP00000211359 antibody
    • OTTHUMP00000211360 antibody
    • OTTHUMP00000211361 antibody
    • OTTHUMP00000211362 antibody
    • OTTHUMP00000211363 antibody
    • ZAN antibody
    • ZAN_HUMAN antibody
    • Zonadhesin antibody
    see all

Anti-ZAN antibody 画像

  • Anti-ZAN antibody (ab118116) at 5 µg/ml + recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 306 kDa
  • ab118116 at 10 µg/ml as a capture antibody. The detection limit for recombinant tagged ZAN is 0.03 ng/ml.

Anti-ZAN antibody (ab118116) 使用論文

ab118116 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"