製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to XYLT1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 551-600 (RITNWNRKLG CKCQYKHIVD WCGCSPNDFK PQDFHRFQQT ARPTFFARKF) of Human XYLT1 (NP_071449).

  • ポジティブ・コントロール
    • PANC1 cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab108263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 108 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.
  • 組織特異性
    Widely expressed. Expressed at higher level in placenta, kidney and pancreas. Weakly expressed in skeletal muscle.
  • パスウェイ
    Glycan metabolism; chondroitin sulfate biosynthesis.
    Glycan metabolism; heparan sulfate biosynthesis.
  • 配列類似性
    Belongs to the glycosyltransferase 14 family. XylT subfamily.
  • 翻訳後修飾
    Contains 7 disulfide bonds.
    N-glycosylated.
  • 細胞内局在
    Endoplasmic reticulum membrane. Golgi apparatus membrane. Secreted. Some fraction is also found in the extracellular space together with chondroitin sulfate proteoglycans, suggesting that it can be secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Beta D xylosyltransferase 1 antibody
    • O xylosyltransferase 1 antibody
    • Peptide O-xylosyltransferase 1 antibody
    • PXYLT1 antibody
    • UDP-D-xylose:proteoglycan core protein antibody
    • XT-I antibody
    • XT1 antibody
    • XTI antibody
    • Xylosyltransferase 1 antibody
    • Xylosyltransferase I antibody
    • xylosyltransferase iota antibody
    • XylT-I antibody
    • XYLT1 antibody
    • XYLT1_HUMAN antibody
    see all

画像

  • Anti-XYLT1 antibody (ab108263) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 108 kDa

プロトコール

参考文献

ab108263 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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