製品の概要

  • 製品名Anti-XTP4 antibody [EPR2678]
    XTP4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2678] to XTP4
  • アプリケーション適用あり: WBmore details
    適用なし: Flow Cyt,ICC,IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human XTP4.

  • ポジティブ・コントロール
    • SKBR3 cell lysate.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名EPR2678
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/1000 - 1/10000. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa).

    Is unsuitable for Flow Cyt, ICC, IHC-P or IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
    • 組織特異性Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).
    • 配列類似性Belongs to the SelWTH family.
    • 翻訳後修飾Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation.
    • 細胞内局在Cytoplasm > cytosol. Cell membrane. Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
    • Information by UniProt
    • 参照データベース
    • 別名
      • C17orf37 antibody
      • C17orf37 homolog antibody
      • C35 antibody
      • chromosome 17 open reading frame 37 antibody
      • HBV X transactivated gene 4 protein antibody
      • HBV X-transactivated gene 4 protein antibody
      • HBV XAg transactivated protein 4 antibody
      • HBV XAg-transactivated protein 4 antibody
      • MGC14832 antibody
      • Mien1 antibody
      • MIEN1_HUMAN antibody
      • Migration and invasion enhancer 1 antibody
      • ORB3 antibody
      • Protein C17orf37 antibody
      • Protein C35 antibody
      • RDX12 antibody
      • Redox protein, 12-KD antibody
      • XTP4 antibody
      see all

    Anti-XTP4 antibody [EPR2678] 画像

    • Anti-XTP4 antibody [EPR2678] (ab92499) at 1/1000 dilution + SKBR3 cell lysate at 10 µg

      Secondary
      goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 12 kDa
      Observed band size : 12 kDa

    Anti-XTP4 antibody [EPR2678] (ab92499) 使用論文

    This product has been referenced in:
    • Nakao LS  et al. Mechanism-based proteomic screening identifies targets of thioredoxin-like proteins. J Biol Chem 290:5685-95 (2015). Read more (PubMed: 25561728) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab92499.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"