製品の概要

  • 製品名Anti-XRN2 antibody
    XRN2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to XRN2
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human, African Green Monkey
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from an internal sequence of human XRN2.

  • ポジティブ・コントロール
    • Human breast carcinoma tissue and COS7 cell extracts.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab74799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/5000.
WB 1/500 - 1/1000. Predicted molecular weight: 109 kDa.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 関連性XRN2 possesses 5'->3' exoribonuclease activity. XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The function of the human gene has not yet been determined, however, it may promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription.
  • 細胞内局在Nucleus, nucleolus.
  • 参照データベース
  • 別名
    • 5' 3' exoribonuclease 2 antibody
    • DHM1 like protein antibody
    • DHP protein antibody
    • XRN 2 antibody

Anti-XRN2 antibody 画像

  • ab74799 at 1/50 dilution staining XRN2 in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.
  • All lanes : Anti-XRN2 antibody (ab74799) at 1/500 dilution

    Lane 1 : COS7 cell extracts
    Lane 2 : COS7 cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 109 kDa
    Observed band size : 109 kDa
    Additional bands at : 40 kDa. We are unsure as to the identity of these extra bands.

Anti-XRN2 antibody (ab74799) 使用論文

ab74799 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"