製品の概要

  • 製品名Anti-XRN2 antibody
    XRN2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to XRN2
  • アプリケーション適用あり: WBmore details
    適用なし: IP
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Tilapia, Orangutan, Xenopus tropicalis , Medaka fish
  • 免疫原

    Synthetic peptide corresponding to a region between residue 1 and 50 of human XRN2 (NP_036387.2)

  • ポジティブ・コントロール
    • Whole cell lysates from HeLa, 293T and NIH3T3 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab72307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/2000 - 1/10000. Detects bands of approximately 109 and 117 kDa (predicted molecular weight: 109 kDa).

    Is unsuitable for IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性XRN2 possesses 5'->3' exoribonuclease activity. XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The function of the human gene has not yet been determined, however, it may promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription.
    • 細胞内局在Nucleus, nucleolus.
    • 参照データベース
    • 別名
      • 5' 3' exoribonuclease 2 antibody
      • DHM1 like protein antibody
      • DHP protein antibody
      • XRN 2 antibody

    Anti-XRN2 antibody 画像

    • All lanes : Anti-XRN2 antibody (ab72307) at 0.04 µg/ml

      Lane 1 : Whole cell lysate from HeLa cells at 50 µg
      Lane 2 : Whole cell lysate from HeLa cells at 15 µg
      Lane 3 : Whole cell lysate from HeLa cells at 5 µg
      Lane 4 : Whole cell lysate from 293T cells at 50 µg
      Lane 5 : Whole cell lysate from NIH 3T3 cells at 50 µg


      Predicted band size : 109 kDa
      Observed band size : 109,117 kDa (why is the actual band size different from the predicted?)

    Anti-XRN2 antibody (ab72307) 使用論文

    ab72307 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab72307.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"