Anti-XRCC3 抗体 (ab97390)

製品の概要

• 製品名
  Anti-XRCC3 antibody
  XRCC3 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to XRCC3
• アプリケーション
  適用あり: WB, ICC/IFmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Recombinant protein fragment contain a sequence corresponding to a region within amino acids 202 and 346 of XRCC3

• ポジティブ･コントロール
  • HepG2 and HeLa cell lines

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• バッファー
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • DNA Damage & Repair
  • Homologous Recomb.

  • Epigenetics and Nuclear Signaling
  • Chromatin Binding Proteins
  • DNA / RNA binding

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • HepG2 nuclear extract lysate (ab14660)
  • HepG2 whole cell lysate (ab7900)

アプリケーション

ターゲット情報

• 機能
  Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.
• 配列類似性
  Belongs to the RecA family. RAD51 subfamily.
• 翻訳後修飾
  Phosphorylated upon DNA damage, probably by ATM or ATR.
• 細胞内局在
  Nucleus. Cytoplasm. Cytoplasm > perinuclear region. Mitochondrion. Accumulates in discrete nuclear foci prior to DNA damage, and these foci persist throughout the time course of DNA repair.

• Target information above from: UniProt accession O43542 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 7517 Human
  • Omim: 600675 Human
  • SwissProt: O43542 Human
  • Unigene: 592325 Human
• 別名
  • CMM6 antibody
  • DNA repair protein XRCC3 antibody
  • RAD51 like antibody

  • X ray repair complementing defective repair in Chinese hamster antibody
  • X ray repair complementing defective repair in Chinese hamster cells 3 antibody
  • X ray repair cross complementing protein 3 antibody
  • X-ray repair cross-complementing protein 3 antibody
  • XRCC 3 antibody
  • XRCC3 antibody
  • XRCC3_HUMAN antibody

  see all

プロトコール

• Western blot protocols
• Immunocytochemistry & immunofluorescence protocols