製品の概要

  • 製品名Anti-XRCC2 antibody [XRCC2 1G4/1]
    XRCC2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [XRCC2 1G4/1] to XRCC2
  • 特異性This antibody is specfic to XRCC2, and does not recognise other paralogs.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Hamster, Human
  • 免疫原

    Recombinant human denatured XRCC2 protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名XRCC2 1G4/1
  • ミエローマSp2/0-Ag14
  • アイソタイプIgG1
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab20253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 34 kDa.

ターゲット情報

  • 機能Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • 配列類似性Belongs to the RecA family. RAD51 subfamily.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp781P0919 antibody
    • DNA repair protein XRCC2 antibody
    • X ray repair complementing defective repair in Chinese hamster cells 2 antibody
    • X ray repair cross complementing protein 2 antibody
    • X-ray repair cross-complementing protein 2 antibody
    • Xrcc2 antibody
    • XRCC2_HUMAN antibody
    see all

Anti-XRCC2 antibody [XRCC2 1G4/1] (ab20253) 使用論文

This product has been referenced in:
  • Xu K  et al. XRCC2 rs3218536 polymorphism decreases the sensitivity of colorectal cancer cells to poly(ADP-ribose) polymerase 1 inhibitor. Oncol Lett 8:1222-1228 (2014). WB ; Human . Read more (PubMed: 25120693) »
  • Gildemeister OS  et al. Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C. J Biol Chem 284:31945-52 (2009). WB ; Human . Read more (PubMed: 19783859) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"