Anti-XPO6 抗体 (ab72333)
Key features and details
- Rabbit polyclonal to XPO6
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-XPO6 antibody
XPO6 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to XPO6 -
由来種
Rabbit -
アプリケーション
適用あり: IPmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis, Platypus -
免疫原
Synthetic peptide from a region between residue 1075 and 1125 of human XPO6, NP_055986.1.
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ポジティブ・コントロール
- Whole cell lysate from Hela cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.09% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab72333の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IP |
特記事項 |
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Is unsuitable for WB. This antibody can be used for WB of enriched sources of XPO6 e.g. immunoprecipitated XPO6, but it has not performed satisfactorily on crude preparations (e.g. whole cell lysate).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Mediates the nuclear export of actin and profilin-actin complexes in somatic cells. -
配列類似性
Belongs to the exportin family.
Contains 1 importin N-terminal domain. -
細胞内局在
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 23214 Human
- Entrez Gene: 74204 Mouse
- Entrez Gene: 293476 Rat
- Omim: 608411 Human
- SwissProt: Q96QU8 Human
- SwissProt: Q924Z6 Mouse
- Unigene: 460468 Human
- Unigene: 235663 Mouse
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別名
- Exp6 antibody
- Exportin 6 antibody
- Exportin-6 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab72333 は 2 報の論文で使用されています。
- McNeill MC et al. Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD. Biochim Biophys Acta Mol Cell Res 1867:118691 (2020). PubMed: 32119877
- Xing B et al. GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in ß cells. J Cell Biol 218:855-870 (2019). PubMed: 30792230