製品の概要

  • 製品名Anti-XPF antibody
    XPF 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to XPF
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 855 and 905 of human XPF (AAB07689.1)

  • ポジティブ・コントロール
    • Human Breast Carcinoma and Prostate Carcinoma tissues.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab84540 was affinity purified using an epitope specific to XPF immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining and is recommended

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link.
    • 関連疾患Defects in ERCC4 are the cause of xeroderma pigmentosum complementation group F (XP-F) [MIM:278760]; also known as xeroderma pigmentosum VI (XP6). XP-F is an autosomal recessive disease characterized by hypersensitivity of the skin to sunlight followed by high incidence of skin cancer and frequent neurologic abnormalities.
      Defects in ERCC4 are a cause of XFE progeroid syndrome (XFEPS) [MIM:610965]. This syndrome is illustrated by one patient who presented with dwarfism, cachexia and microcephaly.
    • 配列類似性Belongs to the XPF family.
      Contains 1 ERCC4 domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DNA excision repair protein ERCC 4 antibody
      • DNA excision repair protein ERCC-4 antibody
      • DNA excision repair protein ERCC4 antibody
      • DNA repair endonuclease XPF antibody
      • DNA repair protein complementing XP F cells antibody
      • DNA repair protein complementing XP-F cells antibody
      • ERCC 11 antibody
      • ERCC 4 antibody
      • ERCC11 antibody
      • ERCC4 antibody
      • Excision repair complementing defective in Chinese hamster antibody
      • Excision repair cross complementing rodent repair deficiency complementation group 4 antibody
      • excision repair cross-complementation group 4 antibody
      • FANCQ antibody
      • RAD 1 antibody
      • RAD1 antibody
      • Xeroderma pigmentosum complementation group F antibody
      • Xeroderma pigmentosum group F complementing protein antibody
      • Xeroderma pigmentosum group F-complementing protein antibody
      • Xeroderma pigmentosum VI antibody
      • XP, group G antibody
      • XP6 antibody
      • XPF_HUMAN antibody
      see all

    Anti-XPF antibody 画像

    • ab84540 at 1/500 dilution staining XPF in human prostate carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    Anti-XPF antibody (ab84540) 使用論文

    ab84540 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84540.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"