Anti-XBP1 抗体 (ab28715)

製品の概要

• 製品名Anti-XBP1 antibody
  XBP1 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to XBP1
• アプリケーション適用あり: WBmore details
• 種交差性
  交差種: Rat, Human
  交差が予測される動物種: Mouse
• 免疫原

  Synthetic peptide conjugated to KLH derived from within residues 200 to the C-terminus of Human XBP1.

  Immunogen の所有権に関して

  (Peptide available as ab30769.)

• ポジティブ･コントロール
  • This antibody gave a positive signal in the following lysates: Jurkat Whole Cell, A431 Whole Cell, Rat Testis Tissue

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• バッファーPreservative: 0.02% Sodium Azide
  Constituents: 1% BSA, PBS. pH 7.4
• Concentration information loading...
• 精製度Immunogen affinity purified
• ポリ/モノポリクローナル
• アイソタイプIgG
• 研究分野
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Other factors

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Transcription Factors

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
• 関連疾患Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.
• 配列類似性Belongs to the bZIP family.
  Contains 1 bZIP domain.
• 細胞内局在Nucleus.

• Target information above from: UniProt accession P17861 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 7494 Human
  • Entrez Gene: 22433 Mouse
  • Entrez Gene: 289754 Rat
  • Omim: 194355 Human
  • SwissProt: P17861 Human
  • SwissProt: O35426 Mouse
  • SwissProt: Q9R1S4 Rat
  • Unigene: 437638 Human

  • Unigene: 469937 Mouse
  • Unigene: 101044 Rat

  see all
• 別名
  • Tax responsive element binding protein 5 antibody
  • Tax-responsive element-binding protein 5 antibody
  • TREB5 antibody

  • X box binding protein 1 antibody
  • X box binding protein 2 antibody
  • X-box-binding protein 1 antibody
  • XBP 1 antibody
  • XBP-1 antibody
  • XBP1 antibody
  • XBP1_HUMAN antibody
  • XBP2 antibody

  see all