製品の概要

  • 製品名Anti-XBP1 antibody [3H1G4]
    XBP1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [3H1G4] to XBP1
  • アプリケーション適用あり: ICC/IF, WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Recombinant protein corresponding to amino acids 2 to 160 of human XBP1

  • ポジティブ・コントロール
    • XBP1 recombinant protein

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab79724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 29 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
  • 関連疾患Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.
  • 配列類似性Belongs to the bZIP family.
    Contains 1 bZIP domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Tax responsive element binding protein 5 antibody
    • Tax-responsive element-binding protein 5 antibody
    • TREB5 antibody
    • X box binding protein 1 antibody
    • X box binding protein 2 antibody
    • X-box-binding protein 1 antibody
    • XBP 1 antibody
    • XBP-1 antibody
    • XBP1 antibody
    • XBP1_HUMAN antibody
    • XBP2 antibody
    see all

Anti-XBP1 antibody [3H1G4] 画像

  • Anti-XBP1 antibody [3H1G4] (ab79724) at 1 µg/ml + XBP1 recombinant protein at 0.1 µg

    Predicted band size : 29 kDa
    Observed band size : 29 kDa
  • Immunofluorescence of XBP1 in HepG2 cells using ab79724 at 4 ug/ml.

Anti-XBP1 antibody [3H1G4] (ab79724) 使用論文

This product has been referenced in:
  • Ortega A  et al. Endoplasmic reticulum stress induces different molecular structural alterations in human dilated and ischemic cardiomyopathy. PLoS One 9:e107635 (2014). WB ; Human . Read more (PubMed: 25226522) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab79724.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"