製品の概要

  • 製品名
  • 製品の詳細
    Mouse polyclonal to WSB1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human protein (entry NP_056441, aa 1-421)

  • ポジティブ・コントロール
    • WSB1-transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab68953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).

ターゲット情報

  • 関連性
    WSB1 is a member of the WD-protein subfamily. It shares a high sequence identity to mouse and chick proteins. It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus. It is a probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It recognizes type II iodothyronine deiodinase/DIO2. There are two named isoforms.
  • 細胞内局在
    Intracellular
  • 参照データベース
  • 別名
    • SOCS box containing WD protein SWiP 1 antibody
    • SWIP1 antibody
    • WD repeat and SOCS box containing 1 antibody
    • WD repeat and SOCS box containing protein 1 antibody
    • WSB 1 antibody
    see all

画像

  • All lanes : Anti-WSB1 antibody (ab68953) at 1/500 dilution

    Lane 1 : WSB1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 47 kDa
    Observed band size : 47 kDa

プロトコール

参考文献

This product has been referenced in:
  • Jia YY  et al. miR-592/WSB1/HIF-1a axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth. Oncotarget 7:35257-69 (2016). WB . Read more (PubMed: 27153552) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab68953.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録