製品の概要

  • 製品名Anti-WISP1 antibody
    WISP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to WISP1
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    CEDDAKRPRKTAPRDT

    conjugated to KLH, corresponding to N terminal amino acids 185-200 of Human WISP1

  • ポジティブ・コントロール
    • Human hepatocarcinom tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab60114 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 関連性WISP1 is a downstream regulator in the Wnt/Frizzled-signaling pathway and is associated with cell survival. WISP1 attentuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase and up-regulates the anti-apoptotic Bcl-X(L) protein. WISP1 is expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Overexpression is associated with several cancers including breast cancer and colon tumors.
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • CCN 4 antibody
    • CCN family member 4 antibody
    • CCN4 antibody
    • WISP 1 antibody
    • WISP 1c antibody
    • WISP 1i antibody
    • WISP 1tc antibody
    • WISP1c antibody
    • WISP1i antibody
    • WISP1tc antibody
    • WNT 1 induced secreted protein 1 antibody
    • Wnt 1 induced secreted protein antibody
    • WNT 1 inducible signaling pathway protein 1 antibody
    • Wnt 1 signaling pathway protein 1 antibody
    • Wnt-1 inducible signaling pathway protein 1 antibody
    • WNT1 induced secreted protein 1 antibody
    • Wnt1 induced secreted protein antibody
    • WNT1 inducible signaling pathway protein 1 antibody
    • Wnt1 signaling pathway protein 1 antibody
    • WNT1-inducible-signaling pathway protein 1 antibody
    see all

Anti-WISP1 antibody 画像

  • Ab60114 (1/50-1/100) staining human WISP1 in human cancer tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

    HC = hepatocarcinoma.

Anti-WISP1 antibody (ab60114) 使用論文

This product has been referenced in:
  • Königshoff M  et al. WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest 119:772-87 (2009). Read more (PubMed: 19287097) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab60114.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"