製品の概要

  • 製品名Anti-WIPF1 antibody
    WIPF1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to WIPF1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Dog
  • 免疫原

    Peptide with sequence

    C-KLARNESRSGSNRRE

    , from the C Terminus of the protein sequence according to NP_003378.3; NP_001070737.1.

  • ポジティブ・コントロール
    • Human Lymph Node, Spleen and Tonsil lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab63944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 51 kDa).

ターゲット情報

  • 機能May have direct activity on the actin cytoskeleton. Induces actin polymerization and redistribution. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus.
  • 組織特異性Highly expressed in peripheral blood mononuclear cells, spleen, placenta, small intestine, colon and thymus. Lower expression in ovary, heart, brain, lung, liver, skeletal muscle, kidney, pancreas, prostate and testis.
  • 配列類似性Belongs to the verprolin family.
    Contains 1 WH2 domain.
  • ドメインBinds to WAS within the N-terminal region 170, at a site distinct from the CDC42-binding site.
  • 細胞内局在Cytoplasmic vesicle. Cytoplasm > cytoskeleton. Vesicle surfaces and along actin tails. Co-localized with actin stress fibers. When co-expressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI115543 antibody
    • D2Ertd120e antibody
    • MGC111041 antibody
    • Protein PRPL-2 antibody
    • PRPL 2 antibody
    • PRPL-2 protein antibody
    • WAS/WASL interacting protein family member 1 antibody
    • WAS/WASL-interacting protein family member 1 antibody
    • WASP-interacting protein antibody
    • WASPIP antibody
    • WIP antibody
    • Wipf1 antibody
    • WIPF1_HUMAN antibody
    • Wiskott-Aldrich syndrome protein interacting protein antibody
    • Wiskott-Aldrich syndrome protein-interacting protein antibody
    see all

Anti-WIPF1 antibody 画像

Anti-WIPF1 antibody (ab63944) 使用論文

ab63944 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"