製品の概要

  • 製品名Anti-WDR8 antibody
    WDR8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to WDR8
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 146-195 (RYLALAERRD CRDYVSIFVC SDWQLLRHFD TDTQDLTGIE WAPNGCVLAA) of Mouse WDR8 (NP_067474.2).

  • ポジティブ・コントロール
    • Mouse brain lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab116245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology (PubMed:26545777). Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles (PubMed:26675238).
  • 組織特異性Ubiquitous. Predominant expression in heart, brain, liver, thymus, prostate, and testis, and barely detectable expression in lung.
  • 配列類似性Contains 6 WD repeats.
  • 細胞内局在Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Enriched in the proximal end of the mother centriole (PubMed:26545777). During ciliogenesis also associated with the basal body of the adjacent centriole (PubMed:26675238).
  • Information by UniProt
  • 参照データベース
  • 別名
    • Dd57 antibody
    • WD repeat domain 8 antibody
    • WD repeat-containing protein 8 antibody
    • WD repeat-containing protein antisense to TP73 gene antibody
    • WD repeat-containing protein WRAP73 antibody
    • WDR8 antibody
    • Wrap73 antibody
    • WRP73_HUMAN antibody
    see all

Anti-WDR8 antibody 画像

  • Anti-WDR8 antibody (ab116245) at 1 µg/ml + Mouse brain lysate at 10 µg

    Predicted band size : 52 kDa

Anti-WDR8 antibody (ab116245) 使用論文

ab116245 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116245.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"