製品の概要

  • 製品名Anti-WAVE 1 antibody
    WAVE 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to WAVE 1
  • 特異性ab59281 detects endogenous levels of total WAVE1 protein.
  • アプリケーション適用あり: IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    A synthesized non phosphopeptide derived from human WAVE1 around the phosphorylation site of tyrosine 125 (ETYPDV).

  • ポジティブ・コントロール
    • Human colon carcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab59281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
ELISA 1/40000.

ターゲット情報

  • 機能Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
  • 組織特異性Highly expressed in brain. Lowly expressed in testis, ovary, colon, kidney, pancreas, thymus, small intestine and peripheral blood.
  • 配列類似性Belongs to the SCAR/WAVE family.
    Contains 1 WH2 domain.
  • ドメインBinds the Arp2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain.
  • 細胞内局在Cytoplasm > cytoskeleton. Dot-like pattern in the cytoplasm. Concentrated in Rac-regulated membrane-ruffling areas.
  • Information by UniProt
  • 参照データベース
  • 別名
    • WASP family, verprolin homology domain-containing protein 1 antibody
    • WASP family member 1 antibody
    • FLJ31482 antibody
    • homology of dictyostelium scar 1 antibody
    • KIAA0269 antibody
    • Protein WAVE-1 antibody
    • Protein WAVE1 antibody
    • scar, Dictyostelium, homology of, 1 antibody
    • SCAR1 antibody
    • Similar to a plant extensin like protein antibody
    • Verprolin homology domain containing protein 1 antibody
    • Verprolin homology domain-containing protein 1 antibody
    • WAS protein family, member 1 antibody
    • Wasf1 antibody
    • WASF1_HUMAN antibody
    • WASL antibody
    • WASP family 1 antibody
    • WASP family protein member 1 antibody
    • WASP family, verprolin homology domain-containing protein antibody
    • WAVE antibody
    • WAVE1 antibody
    • Wiskott Aldrich syndrome protein family member 1 antibody
    • Wiskott-Aldrich syndrome protein family member 1 antibody
    see all

Anti-WAVE 1 antibody 画像

  • Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using ab59281 at a dilution of 1/50. Left hand image - without immunizing peptide; right hand image - with immunizing peptide.

Anti-WAVE 1 antibody (ab59281) 使用論文

ab59281 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"