製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to VRL1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide:

    C-SEEDHLPLQVLQSH

    , corresponding to C terminal amino acids 743-756 of Human VRL1 (NP_035836.2).

  • ポジティブ・コントロール
    • Rat brain lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106829 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 86 kDa).

ターゲット情報

  • 機能
    Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
  • 配列類似性
    Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
    Contains 6 ANK repeats.
  • 翻訳後修飾
    N-glycosylated.
    Phosphorylated by PKA.
  • 細胞内局在
    Cell membrane. Cytoplasm. Melanosome. Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC12549 antibody
    • Osm 9 like TRP channel 2 antibody
    • Osm-9-like TRP channel 2 antibody
    • OTRPC2 antibody
    • Sac2b antibody
    • Stretch activated channel 2B antibody
    • Transient receptor potential cation channel subfamily V member 2 antibody
    • TRPV2 antibody
    • TRPV2_HUMAN antibody
    • Vanilloid receptor like protein 1 antibody
    • Vanilloid receptor-like protein 1 antibody
    • VRL 1 antibody
    • VRL antibody
    • VRL-1 antibody
    • VRL1 antibody
    see all

画像

  • Anti-VRL1 antibody (ab106829) at 2 µg/ml + Rat brain lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 86 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

プロトコール

参考文献

ab106829 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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