製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-QPNVDTRQKQ
    • 領域20 to 29

関連製品

特性

Our Abpromise guarantee covers the use of ab45840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-VPS25 antibody (ab42500)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

関連情報

  • 別名
    • Dermal papilla derived protein 9
    • Dermal papilla-derived protein 9
    • DERP9
    • EAP20
    • ELL associated protein of 20 kDa
    • ELL-associated protein of 20 kDa
    • ESCRT-II complex subunit VPS25
    • FAP20
    • HGNC:28122
    • hVps25
    • MGC10540
    • Vacuolar protein sorting 25 homolog (S. cerevisiae)
    • Vacuolar protein sorting associated protein 25
    • Vacuolar protein-sorting-associated protein 25
    • VPS25
    • VPS25_HUMAN
    see all
  • 機能Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
  • 組織特異性Expressed at the mRNA level in kidney, liver, pancreas, and placenta. Lower levels of expression are found in heart, skeletal muscle, brain and lung.
  • 配列類似性Belongs to the VPS25 family.
  • 細胞内局在Cytoplasm. Endosome membrane. Nucleus > nucleoplasm. Distributes diffusely throughout the cytoplasm and nucleoplasm, but exhibits a punctate distribution on coexpression with CHMP6.
  • Information by UniProt

VPS25 peptide (20-29) (ab45840) 使用論文

ab45840 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"