製品の概要

  • 製品名Anti-Viperin antibody
    Viperin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Viperin
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
    交差が予測される動物種: Rabbit, Horse, Chicken, Turkey, Pig, Chimpanzee, Rhesus monkey, Opossum, Chinese Hamster, Orangutan, Zebra finch, Loxodonta Africana (African bush elephant)
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 165-215 of Human Viperin (NP_542388.2).

  • ポジティブ・コントロール
    • Human brain, Mouse brain and Rat brain lysates, Human rectum tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 3 - 5 µg/ml. Predicted molecular weight: 42 kDa.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.
  • 配列類似性Belongs to the RSAD2 family.
  • 細胞内局在Endoplasmic reticulum membrane. Golgi apparatus. Probably associates with the cytosolic side of the endoplasmic reticulum. Infection with human cytomegalovirus (HCMV) causes relocation to the Golgi apparatus and to cytoplasmic vacuoles which also contain HCMV proteins glycoprotein B and pp28.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2510004L01Rik antibody
    • cig 33 antibody
    • CIG 5 antibody
    • cig-33 antibody
    • CIG-5 antibody
    • CIG33 antibody
    • CIG5 antibody
    • Cytomegalovirus induced gene 5 protein antibody
    • Cytomegalovirus-induced gene 5 protein antibody
    • endoplasmic reticulum-associated antibody
    • interferon-inducible antibody
    • Radical S adenosyl methionine domain containing 2 antibody
    • Radical S-adenosyl methionine domain-containing protein 2 antibody
    • RSAD 2 antibody
    • Rsad2 antibody
    • RSAD2_HUMAN antibody
    • RSDA-2 antibody
    • VIG 1 antibody
    • vig1 antibody
    • Viperin antibody
    • Virus inhibitory protein antibody
    • virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody
    see all

Anti-Viperin antibody 画像

  • All lanes : Anti-Viperin antibody (ab121042) at 3 µg/ml

    Lane 1 : Human brain lysate
    Lane 2 : Human brain lysate with immunizing peptide
    Lane 3 : Mouse brain lysate
    Lane 4 : Rat brain lysate

    Lysates/proteins at 40 µg per lane.

    Secondary
    goat anti-rabbit I HRP
    Developed using the ECL technique

    Predicted band size : 42 kDa
  • Human rectum tissue probed with ab121042 at a concentration of 5 ug/ml.

Anti-Viperin antibody (ab121042) 使用論文

This product has been referenced in:
  • Tateda K  et al. The suppression of TRIM21 and the accumulation of IFN-a play crucial roles in the pathogenesis of osteonecrosis of the femoral head. Lab Invest 92:1318-29 (2012). Rat . Read more (PubMed: 22825687) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"