製品の概要

  • 製品名Anti-VEGFD antibody
    VEGFD 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to VEGFD
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of human VEGFD.

  • ポジティブ・コントロール
    • 293 cell lysate; human lung carcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab63068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/250 - 1/500. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
  • 組織特異性Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
  • 配列類似性Belongs to the PDGF/VEGF growth factor family.
  • 翻訳後修飾Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • c-fos induced growth factor antibody
    • c-fos induced growth factor (vascular endothelial growth factor D) antibody
    • c-fos induced growth factor antibody
    • c-fos-induced growth factor antibody
    • FIGF antibody
    • Vascular endothelial growth factor D antibody
    • Vascular endothelial growth factor D precursor antibody
    • Vascular endothelial growth factor D precursor antibody
    • VEGF D antibody
    • VEGF-D antibody
    • VEGFD antibody
    • VEGFD_HUMAN antibody
    see all

Anti-VEGFD antibody 画像

  • Anti-VEGFD antibody (ab63068) at 1/250 dilution + 293 cell lysate at 12.5 µg

    Predicted band size : 40 kDa
    Observed band size : 40 kDa
    Additional bands at : 72 kDa. We are unsure as to the identity of these extra bands.
  • Ab63068 (1/50-1/100) staining human VEGFD in human lung carcinoma tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

    Ab63068 was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-VEGFD antibody (ab63068) 使用論文

ab63068 has not yet been referenced specifically in any publications.

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