Anti-VEGFB 抗体 [EPR4555] (ab110649)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4555] to VEGFB
- Suitable for: WB
- Reacts with: Recombinant fragment
Related conjugates and formulations
製品の概要
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製品名
Anti-VEGFB antibody [EPR4555]
VEGFB 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR4555] to VEGFB -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: ICC/IF,IHC-P or IP -
種交差性
交差種: Recombinant fragment
交差が予測される動物種: Mouse, Rat, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- VEGFB recombinant protein
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR4555 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab110649の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 19 kDa (predicted molecular weight: 22 kDa).
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特記事項 |
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WB
1/1000 - 1/10000. Detects a band of approximately 19 kDa (predicted molecular weight: 22 kDa). |
ターゲット情報
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機能
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. -
組織特異性
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. -
配列類似性
Belongs to the PDGF/VEGF growth factor family. -
翻訳後修飾
VEGF-B186 is O-glycosylated. -
細胞内局在
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. - Information by UniProt
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参照データベース
- Entrez Gene: 7423 Human
- Entrez Gene: 22340 Mouse
- Entrez Gene: 89811 Rat
- Omim: 601398 Human
- SwissProt: P49765 Human
- SwissProt: P49766 Mouse
- SwissProt: O35485 Rat
- Unigene: 78781 Human
see all -
製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- Vascular endothelial growth factor B antibody
- Vascular endothelial growth factor-related factor antibody
- VEGF B antibody
see all
画像
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Anti-VEGFB antibody [EPR4555] (ab110649) at 1/1000 dilution + VEGFB recombinant protein at 10 µg
Secondary
HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 22 kDa
Observed band size: 19 kDa why is the actual band size different from the predicted?
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab110649 は 2 報の論文で使用されています。
- Park Y et al. Impact of Exogenous Treatment with Histidine on Hepatocellular Carcinoma Cells. Cancers (Basel) 14:N/A (2022). PubMed: 35267513
- Tan Q et al. VEGF-B targeting by aryl hydrocarbon receptor mediates the migration and invasion of choriocarcinoma stem-like cells. Cancer Cell Int 22:221 (2022). PubMed: 35773697