製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to VEGFB
  • 特異性
    Anti-human VEGFB exhibits less than 5% cross-reactivity with recombinant human VEGFD and no cross-reactivity with recombinant human VEGF and recombinant mouse VEGF.
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant full length VEGFB 186 (Human), expressed in E. coli.

  • 特記事項
    Do not store in a frost-free freezer. Endotoxin level is < 30 ng/mg antibody as determined by the LAL (Limulus amebocyte lysate) method.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab10965 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報
    ELISA: Use at a concentration of 0.5 - 1 µg/ml. The detection limit for recombinant human VEGFB 167 is approximately 0.3 ng/well. The detection limit for recombinant human VEGFB 186 is approximately 0.03 ng/well.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant human VEGFB 167 is approximately 25 ng/lane under non-reducing and reducing conditions. The detection limit for recombinant human VEGFB 186 is approximately 5 ng/lane under non-reducing and reducing conditions. Predicted molecular weight: 22 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
    • 組織特異性
      Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
    • 配列類似性
      Belongs to the PDGF/VEGF growth factor family.
    • 翻訳後修飾
      VEGF-B186 is O-glycosylated.
    • 細胞内局在
      Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
    • Information by UniProt
    • 参照データベース
    • 製品の状態
      There are 2 isoforms produced by alternative splicing.
    • 別名
      • Vascular endothelial growth factor B antibody
      • Vascular endothelial growth factor-related factor antibody
      • VEGF B antibody
      • VEGF related factor antibody
      • VEGF-B antibody
      • VEGF-related factor antibody
      • Vegfb antibody
      • VEGFB_HUMAN antibody
      • VEGFL antibody
      • VRF antibody
      see all

    プロトコール

    Anti-VEGFB antibody (ab10965) 使用論文

    ab10965 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab10965.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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