製品の概要

  • 製品名Anti-VEGF Receptor 3 antibody [44CT92.4.4]
    VEGF Receptor 3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [44CT92.4.4] to VEGF Receptor 3
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponding to Human VEGF Receptor 3.

  • ポジティブ・コントロール
    • VGFR3 recombinant fragment and human lung carcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab72240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Detects a band of approximately 50 kDa (predicted molecular weight: 146 kDa).
ELISA 1/1000.
IHC-P 1/10 - 1/50.

ターゲット情報

  • 機能Receptor for VEGFC. Has a tyrosine-protein kinase activity.
  • 組織特異性Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain.
  • 関連疾患Defects in FLT4 are the cause of lymphedema hereditary type 1A (LMPH1A) [MIM:153100]; also known as Nonne-Milroy lymphedema or Milroy disease. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections and physical impairment.
    Note=Defects in FLT4 are found in juvenile hemangioma. Juvenile hemangiomas are the most common tumors of infancy, occurring as many as 10% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes, and then spontaneously involute over a period of years, leaving loose fibrofatty tissue.
  • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EC 2.7.10.1 antibody
    • flt 4 antibody
    • FLT-4 antibody
    • FLT4 antibody
    • FLT41 antibody
    • Fms related tyrosine kinase 4 antibody
    • Fms-like tyrosine kinase 4 antibody
    • LMPH1A antibody
    • PCL antibody
    • Soluble VEGFR3 variant 1 antibody
    • Soluble VEGFR3 variant 2 antibody
    • Soluble VEGFR3 variant 3 antibody
    • Tyrosine protein kinase receptor FLT4 antibody
    • Tyrosine-protein kinase receptor FLT4 antibody
    • Vascular endothelial growth factor receptor 3 antibody
    • Vascular endothelial growth factor receptor 3 precursor antibody
    • VEGF R3 antibody
    • VEGFR 3 antibody
    • VEGFR-3 antibody
    • VEGFR3 antibody
    • VGFR3_HUMAN antibody
    see all

Anti-VEGF Receptor 3 antibody [44CT92.4.4] 画像

  • Anti-VEGF Receptor 3 antibody [44CT92.4.4] (ab72240) at 1/2000 dilution + VGFR3 recombinant fragment

    Predicted band size : 146 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
  • ab72240 at 1/10 dilution, staining VEGF Receptor 3 in human lung carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-VEGF Receptor 3 antibody [44CT92.4.4] (ab72240) 使用論文

This product has been referenced in:
  • Singh N  et al. Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity. Blood 121:4242-9 (2013). Mouse . Read more (PubMed: 23476047) »

See 1 Publication for this product

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step H2O2 as blocking agent for 10 minute(s) · Concentration: 3% · Temperature: 25°C
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate, pH6, 100C, 20min
Sample Human Tissue sections (angiosarcoma)
Specification angiosarcoma
Permeabilization No
Fixative Formaldehyde
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投稿 Sep 12 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"