製品の概要

  • 製品名
    Anti-VCAM1 antibody [MVCAM.A(429)] (FITC)
    VCAM1 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [MVCAM.A(429)] to VCAM1 (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Stromal cell line PA6

  • 特記事項


    Clone MVCAM.A(429) is reported to partially block VCAM-1 mediated functions (Kinashi, T. and Springer, T.A. (1994)).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab23807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt 1/50 - 1/100.

Use 10µl of the suggested working dilution to label 106 cells in 100µl.





ab18446-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 組織特異性
    Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 配列類似性
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • ドメイン
    Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻訳後修飾
    Sialoglycoprotein.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

プロトコール

参考文献

This product has been referenced in:

See 1 Publication for this product

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