製品の概要

  • 製品名Anti-VCAM1 antibody [MVCAM.A(429)]
    VCAM1 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [MVCAM.A(429)] to VCAM1
  • アプリケーション適用あり: Flow Cyt, IHC-Frmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Tissue/ cell preparation (Mouse) - Stromal cell line PA6.

  • 特記事項


    This antibody is reported to partially block VCAM1 mediated functions.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab27560 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt 1/100 - 1/200. Use 10µl of the suggested working dilution to label 106 cells in 100µl.



ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 機能Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 組織特異性Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 配列類似性Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • ドメインEither the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻訳後修飾Sialoglycoprotein.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

Anti-VCAM1 antibody [MVCAM.A(429)] (ab27560) 使用論文

This product has been referenced in:
  • Mikkelsen HB  et al. The macrophage system in the intestinal muscularis externa during inflammation: an immunohistochemical and quantitative study of osteopetrotic mice. Histochem Cell Biol 130:363-73 (2008). IHC-Fr ; Mouse . Read more (PubMed: 18392842) »

See 1 Publication for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (ileum (small intestine) treated with lipopolysacch)
Specification ileum (small intestine) treated with lipopolysacch
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 10% in TBS
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投稿 May 23 2007

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"