Anti-VCAM1 抗体 [MR106] (Biotin) (ab95542)

製品の概要

  • 製品名
    Anti-VCAM1 antibody [MR106] (Biotin)
    VCAM1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MR106] to VCAM1 (Biotin)
  • 標識
    Biotin
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Rat VCAM1 transfected L5178Y cells.

  • ポジティブ・コントロール
    • Rat bone marrow cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab95542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.125-0.25µg for 105-8 cells.

A final volume of 100 µL is recommended for staining the cell sample.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能
    Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 組織特異性
    Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 配列類似性
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • ドメイン
    Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻訳後修飾
    Sialoglycoprotein.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

画像

  • Staining of Rat bone marrow cells with 0.125 µg of Mouse IgG1 ? Isotype Control Biotin (left) or 0.125 µg of ab95542 (right), followed by Streptavidin PE.
    Total viable cells were used for analysis.

プロトコール

参考文献

ab95542 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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