製品の概要

  • 製品名
    Anti-VCAM1 antibody (Biotin)
    VCAM1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to VCAM1 (Biotin)
  • 由来種
    Rabbit
  • 標識
    Biotin
  • アプリケーション
    適用あり: WB, Sandwich ELISAmore details
  • 種交差性
    交差種: Recombinant fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 25-697 of Human VCAM1

  • 特記事項
    The lyophilized antibody is stable for at least 2 years from date of receipt at -20oC. The reconstituted antibody is stable for at least two weeks at 2-8oC. Frozen aliquots are stable for at least 6 months when stored at -20oC. Avoid repeated freeze-thaw cycles.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 81 kDa.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml.

ターゲット情報

  • 機能
    Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 組織特異性
    Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 配列類似性
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • ドメイン
    Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻訳後修飾
    Sialoglycoprotein.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

プロトコール

参考文献

ab107519 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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