製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to VCAM1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 294-322 of Human VCAM1 (NP_001069.1, NP_542413.1).

  • ポジティブ・コントロール
    • HepG2 and NIH 3T3 lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab123801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Predicted molecular weight: 81 kDa.

ターゲット情報

  • 機能
    Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 組織特異性
    Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 配列類似性
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • ドメイン
    Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻訳後修飾
    Sialoglycoprotein.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

画像

  • Anti-VCAM1 antibody (ab123801) at 1/50 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 81 kDa
  • Anti-VCAM1 antibody (ab123801) at 1/50 dilution + Mouse NIH 3T3 cell line lysates

    Predicted band size : 81 kDa

プロトコール

参考文献

ab123801 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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