製品の概要

  • 製品名Anti-VAV2 (phospho Y172) antibody
    VAV2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to VAV2 (phospho Y172)
  • 特異性ab86695 detects Vav1, Vav2, and Vav3 in Jurkat cells treated with pervanadate. The antibody does not detect these Vavs after treatment with alkaline phosphatase.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH corresponding to amino acid residues surrounding Tyr-172 in human VAV2. This sequence has high homology with similar regions in rat and mouse VAV2, and has significant homology to the conserved site in Vav1 and Vav3.

  • ポジティブ・コントロール
    • A431 cells treated with EGF.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Detects a band of approximately 101 kDa (predicted molecular weight: 101 kDa).
ELISA 1/2000.

ターゲット情報

  • 機能Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
  • 組織特異性Widely expressed.
  • 配列類似性Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Guanine nucleotide exchange factor VAV2 antibody
    • Oncogene VAV2 antibody
    • Protein vav 2 antibody
    • VAV 2 antibody
    • Vav 2 oncogene antibody
    • VAV-2 antibody
    • VAV2 antibody
    • VAV2 oncogene antibody
    • VAV2_HUMAN antibody
    see all

Anti-VAV2 (phospho Y172) antibody 画像

  • All lanes : Anti-VAV2 (phospho Y172) antibody (ab86695) at 1/1000 dilution

    Lane 1 : A431 cells treated with EGF
    Lane 2 : A431 cells treated with EGF, exposed to alkaline phosphatase


    Predicted band size : 101 kDa
    Observed band size : 101 kDa
    Additional bands at : <100 kDa. We are unsure as to the identity of these extra bands.

Anti-VAV2 (phospho Y172) antibody (ab86695) 使用論文

This product has been referenced in:
  • Espejo R  et al. PTP-PEST targets a novel tyrosine site in p120 catenin to control epithelial cell motility and Rho GTPase activity. J Cell Sci 127:497-508 (2014). Read more (PubMed: 24284071) »
  • Havel LS  et al. Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity. Oncogene N/A:N/A (2014). Human . Read more (PubMed: 24858039) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab86695.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"