製品の概要

  • 製品名Anti-VAP1 antibody
    VAP1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to VAP1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Orangutan
  • 免疫原

    Synthetic peptide:

    C-DEDPSFYSADSIY

    , corresponding to internal sequence amino acids 712-724 of Human VAP1

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab59037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Preliminary experiments gave an approx 55kDa band in Human Adipose and Lung lysates after 0.01µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 84.6kDa according to NP_003725.1. The 55kDa band was successfully blocked by incubation with the immunizing peptide.
IHC-P Use a concentration of 3 - 5 µg/ml. In paraffin embedded Human Liver shows membranous staining in sinusoid lining cells surrounding hepatocytes.

ターゲット情報

  • 機能Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
  • 組織特異性Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
  • 配列類似性Belongs to the copper/topaquinone oxidase family.
  • 翻訳後修飾Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
    N- and O-glycosylated.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
    • AOC3 antibody
    • AOC3_HUMAN antibody
    • Copper amine oxidase antibody
    • HPAO antibody
    • Membrane copper amine oxidase antibody
    • Membrane primary amine oxidase antibody
    • Semicarbazide sensitive amine oxidase antibody
    • Semicarbazide-sensitive amine oxidase antibody
    • SSAO antibody
    • VAP-1 antibody
    • Vascular adhesion protein 1 antibody
    • VP97 antibody
    see all

Anti-VAP1 antibody 画像

  • ab59037 at 1 µg/ml staining VAP1 in Human liver tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6 was performed. Antibody detected with AP-staining.

Anti-VAP1 antibody (ab59037) 使用論文

ab59037 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"