Anti-VAP1 抗体 [7-88] (ab81673)
Key features and details
- Rat monoclonal [7-88] to VAP1
- Suitable for: IHC-Fr
- Reacts with: Mouse
- Isotype: IgG2b
製品の概要
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製品名
Anti-VAP1 antibody [7-88]
VAP1 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [7-88] to VAP1 -
由来種
Rat -
アプリケーション
適用あり: IHC-Frmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse VAP1.
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ポジティブ・コントロール
- Mouse spleen Mouse VAP-1-transfected CHO cells
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特記事項
Inhibits migration of granulocytes and monocytes in acute models of inflammation.
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製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Constituents: 1% BSA, PBS -
Concentration information loading...
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精製度
Protein A purified -
一次抗体 備考
Inhibits migration of granulocytes and monocytes in acute models of inflammation. -
ポリ/モノ
モノクローナル -
クローン名
7-88 -
アイソタイプ
IgG2b -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab81673の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-Fr |
1/50.
|
特記事項 |
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IHC-Fr
1/50. |
ターゲット情報
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機能
Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. -
組織特異性
Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. -
配列類似性
Belongs to the copper/topaquinone oxidase family. -
翻訳後修飾
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
N- and O-glycosylated. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 11754 Mouse
- SwissProt: O70423 Mouse
- Unigene: 67281 Mouse
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別名
- Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
- AOC3 antibody
- AOC3_HUMAN antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab81673 は 7 報の論文で使用されています。
- Dong H et al. Identification of a regulatory pathway inhibiting adipogenesis via RSPO2. Nat Metab 4:90-105 (2022). PubMed: 35027768
- Hu Q et al. MicroRNA-137 exerts protective effects on hypoxia-induced cell injury by inhibiting autophagy/mitophagy and maintaining mitochondrial function in breast cancer stem-like cells. Oncol Rep 44:1627-1637 (2020). PubMed: 32945512
- Schwalie PC et al. A stromal cell population that inhibits adipogenesis in mammalian fat depots. Nature 559:103-108 (2018). PubMed: 29925944
- Yoshikawa N et al. Blockade of vascular adhesion protein-1 attenuates choroidal neovascularization. Mol Vis 18:593-600 (2012). ICC/IF ; Mouse . PubMed: 22419852
- Merinen M et al. Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse. Am J Pathol 166:793-800 (2005). Flow Cyt, Functional Studies, IHC-Fr ; Mouse . PubMed: 15743791
- Bonder CS et al. Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1. Immunity 23:153-63 (2005). IHC-Fr ; Mouse . PubMed: 16111634
- Abella A et al. Adipocytes release a soluble form of VAP-1/SSAO by a metalloprotease-dependent process and in a regulated manner. Diabetologia 47:429-38 (2004). IP ; Mouse . PubMed: 14968297