製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to VANGL2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide:

    C-QKYLRTTKQQPYH

    , corresponding to internal sequence amino acids 403-415 of Human VANGL2

  • ポジティブ・コントロール
    • WB: Mouse brain tissue lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab60172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa).

ターゲット情報

  • 機能
    Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.
  • 配列類似性
    Belongs to the Vang family.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Homolog of Drosophila strabismus antibody
    • KIAA1215 antibody
    • Loop tail associated protein antibody
    • loop tail protein 1 homolog antibody
    • Loop-tail protein 1 homolog antibody
    • LPP 1 antibody
    • LPP1 antibody
    • LTAP antibody
    • MGC119403 antibody
    • MGC119404 antibody
    • STB 1 antibody
    • STB1 antibody
    • STBM 1 antibody
    • STBM antibody
    • STBM1 antibody
    • Strabismus 1 antibody
    • van Gogh like protein 2 antibody
    • Van Gogh-like protein 2 antibody
    • Vang (van gogh, Drosophila) like 2 antibody
    • Vang like 2 (van gogh, Drosophila) antibody
    • vang like 2 antibody
    • vang like protein 2 antibody
    • Vang-like protein 2 antibody
    • VANG2_HUMAN antibody
    • VANGL 2 antibody
    • VANGL planar cell polarity protein 2 antibody
    • Vangl2 antibody
    see all

Anti-VANGL2 antibody 画像

プロトコール

Anti-VANGL2 antibody (ab60172) 使用論文

This product has been referenced in:
  • Li H  et al. miR-542-3p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogh-like 2. Mol Med Rep 11:851-6 (2015). WB ; Human . Read more (PubMed: 25352048) »

See 1 Publication for this product

Product Wall

Application
Western blot
Loading amount
10 µg
Gel Running Conditions
Non-reduced Non-Denaturing (Native)
Sample
Zebrafish Tissue lysate - whole (whole embryo)
Specification
whole embryo
Blocking step
BSA as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Abcam user community

Verified customer

投稿 Feb 05 2015

Application
Immunohistochemistry (Frozen sections)
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5%
Sample
Mouse Tissue sections (Adult Female reproductive - Ovary/Oviduct/Uterus)
Specification
Adult Female reproductive - Ovary/Oviduct/Uterus
Permeabilization
Yes - PBST (PBS/0.1% v/v TritonX100 (sigma))
Fixative
TCA
Username

Ms. Julia Watson

Verified customer

投稿 Nov 24 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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