Anti-VANGL2 抗体 (ab60172)
Key features and details
- Goat polyclonal to VANGL2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-VANGL2 antibody
VANGL2 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to VANGL2 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat, Xenopus laevis, Zebrafish -
免疫原
Synthetic peptide:
C-QKYLRTTKQQPYH
, corresponding to internal sequence amino acids 403-415 of Human VANGL2 -
ポジティブ・コントロール
- WB: Mouse brain tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab60172の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (1) |
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa).
1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa). 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. -
配列類似性
Belongs to the Vang family. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 93840 Mouse
- Entrez Gene: 289229 Rat
- Entrez Gene: 245949 Zebrafish
- SwissProt: Q91ZD4 Mouse
- SwissProt: P84889 Rat
- SwissProt: Q8UVJ6 Zebrafish
- Unigene: 36148 Mouse
- Unigene: 392110 Mouse
see all -
別名
- Homolog of Drosophila strabismus antibody
- KIAA1215 antibody
- Loop tail associated protein antibody
see all
画像
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Anti-VANGL2 antibody (ab60172) at 0.3 µg/ml + Mouse Brain lysate (35µg protein in RIPA buffer)
Predicted band size: 60 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour. Detected by chemiluminescence.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab60172 は 1 報の論文で使用されています。
- Li H et al. miR-542-3p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogh-like 2. Mol Med Rep 11:851-6 (2015). WB ; Human . PubMed: 25352048