製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to VANGL1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide corresponding to a region between residues 350-400 of human VANGL1 isoform 2 (NP_620409)

  • ポジティブ・コントロール
    • Lysates from HCT-116 and RAW cells.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.05% Sodium Azide
    Constituents: 0.05% BSA, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab72332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 3 - 5 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 60 kDa).

ターゲット情報

  • 組織特異性
    Accordiing to PubMed:11956595, ubiquitously expressed. According to PubMed:12011995, expressed specifically in testis and ovary.
  • 関連疾患
    Defects in VANGL1 are a cause of neural tube defects (NTD) [MIM:182940]. NTD are congenital malformations. The most common forms of NTD are described as open defects (including anencephaly and myelomeningocele, or spina bifida), which result from the failure of fusion in the cranial and spinal region of the neural tube, respectively. Other open dysraphisms (including myeloschisis, hemimyelomeningocele, and hemimyelocele) are sometimes associated with a Chiari type 2 malformation. A number of skin-covered (closed) NTD are categorized clinically depending on the presence of a subcutaneous mass (lipomyeloschisis, lipomyelomeningocele, meningocele, and myelocystocele) or the absence of such a mass (complex dysraphic states, including split cord malformations, dermal sinus, caudal regression, and segmental spinal dysgenesis).
    Defects in VANGL1 are a cause of sacral defect with anterior meningocele (SDAM) [MIM:600145]. SDAM is a form of caudal dysgenesis. It is present at birth and becomes symptomatic later in life, usually because of obstructive labor in females, chronic constipation, or meningitis. Inheritance is autosomal dominant.
  • 配列類似性
    Belongs to the Vang family.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANGL planar cell polarity protein 1 antibody
    • KAI1 C-terminal interacting tetraspanin antibody
    • KITENIN antibody
    • Loop tail protein 2 homolog antibody
    • Loop-tail protein 2 homolog antibody
    • LPP2 antibody
    • MGC5338 antibody
    • STB2 antibody
    • STBM2 antibody
    • Strabismus 2 antibody
    • Strabismus, Drosophila, homolog of, 2 antibody
    • Van Gogh like protein 1 antibody
    • Van Gogh, Drosophila, homolog of, 1 antibody
    • Van Gogh-like protein 1 antibody
    • Vang like 1 (van gogh, Drosophila) antibody
    • Vang like protein 1 antibody
    • Vang-like 1 antibody
    • Vang-like protein 1 antibody
    • VANG1_HUMAN antibody
    • VANGL 1 antibody
    • Vangl1 antibody
    see all

Anti-VANGL1 antibody 画像

  • All lanes : Anti-VANGL1 antibody (ab72332) at 4 µg/ml

    Lane 1 : HCT-116 cell lysate
    Lane 2 : HCT-116 cell lysate with immunizing peptide
    Lane 3 : RAW cell lysate


    Predicted band size : 60 kDa
    Observed band size : 60 kDa
    Additional bands at : 160 kDa,45 kDa. We are unsure as to the identity of these extra bands.

プロトコール

Anti-VANGL1 antibody (ab72332) 使用論文

ab72332 has not yet been referenced specifically in any publications.

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