製品の概要

  • 製品名Anti-VANGL1 antibody
    VANGL1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to VANGL1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human VANGL1 protein (NP_620409.1).

  • ポジティブ・コントロール
    • VANGL1 transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab69227 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 60 kDa).

ターゲット情報

  • 組織特異性Accordiing to PubMed:11956595, ubiquitously expressed. According to PubMed:12011995, expressed specifically in testis and ovary.
  • 関連疾患Defects in VANGL1 are a cause of neural tube defects (NTD) [MIM:182940]. NTD are congenital malformations. The most common forms of NTD are described as open defects (including anencephaly and myelomeningocele, or spina bifida), which result from the failure of fusion in the cranial and spinal region of the neural tube, respectively. Other open dysraphisms (including myeloschisis, hemimyelomeningocele, and hemimyelocele) are sometimes associated with a Chiari type 2 malformation. A number of skin-covered (closed) NTD are categorized clinically depending on the presence of a subcutaneous mass (lipomyeloschisis, lipomyelomeningocele, meningocele, and myelocystocele) or the absence of such a mass (complex dysraphic states, including split cord malformations, dermal sinus, caudal regression, and segmental spinal dysgenesis).
    Defects in VANGL1 are a cause of sacral defect with anterior meningocele (SDAM) [MIM:600145]. SDAM is a form of caudal dysgenesis. It is present at birth and becomes symptomatic later in life, usually because of obstructive labor in females, chronic constipation, or meningitis. Inheritance is autosomal dominant.
  • 配列類似性Belongs to the Vang family.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ANGL planar cell polarity protein 1 antibody
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    • Loop-tail protein 2 homolog antibody
    • LPP2 antibody
    • MGC5338 antibody
    • STB2 antibody
    • STBM2 antibody
    • Strabismus 2 antibody
    • Strabismus, Drosophila, homolog of, 2 antibody
    • Van Gogh like protein 1 antibody
    • Van Gogh, Drosophila, homolog of, 1 antibody
    • Van Gogh-like protein 1 antibody
    • Vang like 1 (van gogh, Drosophila) antibody
    • Vang like protein 1 antibody
    • Vang-like 1 antibody
    • Vang-like protein 1 antibody
    • VANG1_HUMAN antibody
    • VANGL 1 antibody
    • Vangl1 antibody
    see all

Anti-VANGL1 antibody 画像

  • All lanes : Anti-VANGL1 antibody (ab69227) at 1/500 dilution

    Lane 1 : VANGL1 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 60 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)

Anti-VANGL1 antibody (ab69227) 使用論文

ab69227 has not yet been referenced specifically in any publications.

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