The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: Use at an assay dependant dilution.
WB: 1/200 - 1/2000.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.
配列類似性Belongs to the synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain.
細胞内局在Golgi apparatus > trans-Golgi network membrane. Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.
Vesicle associated membrane protein 4 isoform CRA a antibody
Vesicle associated membrane protein 4 isoform CRA b antibody
Vesicle-associated membrane protein 4 antibody
Anti-VAMP4 antibody (ab6185) 使用論文
This product has been referenced in:
Colombo F et al. Neurite outgrowth induced by NGF or L1CAM via activation of the TrkA receptor is sustained also by the exocytosis of enlargeosomes. Proc Natl Acad Sci U S A111:16943-8 (2014).
Read more (PubMed: 25385598) »
Lieu ZZ et al. The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network. Mol Biol Cell18:4979-91 (2007).
Read more (PubMed: 17914056) »