Anti-Valproic Acid 抗体 [10-201.7] (ab40988)

製品の概要

  • 製品名Anti-Valproic Acid antibody [10-201.7]
    Valproic Acid 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [10-201.7] to Valproic Acid
  • 特異性Specifically recognizes valproic acid.
  • アプリケーション適用あり: ELISAmore details
  • 免疫原

    Valproic acid conjugated to KLH.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名10-201.7
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab40988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
  • 追加情報ELISA: 1/51200.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
    Dilute in PBS or medium which is identical to that used in the assay system.
  • ターゲット情報

    • 関連性Valproic acid, valproate sodium and divalproex belong to the group of medicines called anticonvulsants, used to control certain types of seizures in the treatment of epilepsy. Also, valproic acid relieves histone deacetylases (HDACs) dependent transcriptional repression and causes hyperacetylation of histones in cultured cells and in vivo. Valproic acid inhibits HDAC activity in vitro, most probably by binding to the catalytic centre of HDACs. Most importantly, valproic acid induces differentiation of carcinoma cells, transformed haematopoietic progenitor cells and leukaemic blasts from acute myeloid leukaemia patients. Moreover, tumour growth and metastasis formation are significantly reduced in animal experiments. Therefore, valproic acid might serve as an effective drug for cancer therapy.
    • 別名
      • 2methylbutyryl coa dehydrogenase antibody
      • 2methylbutyryl coenzyme a dehydrogenase antibody

    Anti-Valproic Acid antibody [10-201.7] (ab40988) 使用論文

    ab40988 has not yet been referenced specifically in any publications.

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    Thank you for contacting us.

    Yes, I can confirm that the ab40988 is able to recognize free valproic acid, therefore the ab120745. The laboratory confirmed indeed that this antibody has been used in a competitive immunoassay in which antibody...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"