製品の概要

  • 製品名
  • 製品の詳細
    Mouse polyclonal to USP46
  • アプリケーション
    適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human USP46 protein (NP_073743.2).

  • ポジティブ・コントロール
    • Human kidney tissue lysate. USP46 transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88795 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.
ICC/IF Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
  • 組織特異性
    Broadly expressed.
  • 配列類似性
    Belongs to the peptidase C19 family. USP12/USP46 subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Deubiquitinating enzyme 46 antibody
    • FLJ11850 antibody
    • FLJ12552 antibody
    • FLJ14283 antibody
    • FLJ39393 antibody
    • Ubiquitin carboxyl terminal hydrolase 46 antibody
    • Ubiquitin carboxyl-terminal hydrolase 46 antibody
    • Ubiquitin specific peptidase 46 antibody
    • Ubiquitin specific processing protease 46 antibody
    • Ubiquitin specific protease 46 antibody
    • Ubiquitin thioesterase 46 antibody
    • Ubiquitin thiolesterase 46 antibody
    • Ubiquitin-specific-processing protease 46 antibody
    • UBP46_HUMAN antibody
    • USP46 antibody
    see all

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参考文献

ab88795 has not yet been referenced specifically in any publications.

レビューと Q&A

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cultured Cells (MCF7)
Specification
MCF7
Fixative
Paraformaldehyde
Permeabilization
Yes - 0.5% triton-x 10min
Blocking step
BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 24°C
Username

Abcam user community

Verified customer

投稿 Nov 08 2010

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Western blot
Sample
Human Cell lysate - other (HELA)
Loading amount
30 µg
Specification
HELA
Gel Running Conditions
Reduced Denaturing
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 24°C
Username

Abcam user community

Verified customer

投稿 Nov 08 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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