製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to USP4
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Chinese hamster, Orangutan, Bat
  • 免疫原

    Synthetic peptide corresponding to a region between residue 225 and 275 of human USP4

  • ポジティブ・コントロール
    • HeLa whole cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP
  • 追加情報
    IP: Use at 2-5µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. Plays a role in the regulation of quality control in the ER.
    • 組織特異性
      Overexpressed in small cell tumors and adenocarcinomas of the lung compared to wild-type lung (at protein level). Expressed in the hippocampal neurons.
    • 配列類似性
      Belongs to the peptidase C19 family. USP4 subfamily.
      Contains 1 DUSP domain.
    • 翻訳後修飾
      Monoubiquitinated by TRIM21. Ubiquitination does not lead to its proteasomal degradation. Autodeubiquitinated.
    • 細胞内局在
      Cytoplasm. Nucleus. Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The relative amounts found in the nucleus and cytoplasm vary according to the cell type.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Deubiquitinating enzyme 4 antibody
      • MGC149848 antibody
      • MGC149849 antibody
      • Proto oncogene antibody
      • Protooncogene antibody
      • Ubiquitin carboxyl terminal hydrolase 4 antibody
      • Ubiquitin carboxyl-terminal hydrolase 4 antibody
      • Ubiquitin specific peptidase 4 (proto oncogene) antibody
      • Ubiquitin specific peptidase 4 (protooncogene) antibody
      • Ubiquitin specific peptidase 4 antibody
      • Ubiquitin specific processing protease 4 antibody
      • Ubiquitin specific protease 4 (proto oncogene) antibody
      • Ubiquitin specific protease 4 (protooncogene) antibody
      • Ubiquitin specific protease 4 antibody
      • Ubiquitin specific protease proto oncogene antibody
      • Ubiquitin specific protease protooncogene antibody
      • Ubiquitin thioesterase 4 antibody
      • Ubiquitin thiolesterase 4 antibody
      • Ubiquitin-specific-processing protease 4 antibody
      • Ubiquitous nuclear protein homolog antibody
      • UBP4_HUMAN antibody
      • UNP antibody
      • UNPH antibody
      • USP 4 antibody
      • USP4 antibody
      see all

    画像

    • Detection of Human USP4 by Western Blot of Immunprecipitate. ab70617 at 1µg/ml staining USP4 (approximately 120kDa) in HeLa whole cell lysates immunoprecipitated using ab70617 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).Detection: Chemiluminescence with an exposure time of 30 seconds.

    プロトコール

    参考文献

    ab70617 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab70617.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録