Anti-USP2 抗体 - Aminoterminal end (ab71796)

製品の概要

  • 製品名Anti-USP2 antibody - Aminoterminal end
    USP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to USP2 - Aminoterminal end
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the N-terminal region of human USP2.

  • ポジティブ・コントロール
    • HL60 cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab71796 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Detects a band of approximately 68 kDa plus a range of other bands. (predicted molecular weight: 68 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells.
    • 組織特異性Expressed in mesangial cells of the kidney and in different types of glomerulonephritides (at protein level).
    • 配列類似性Belongs to the peptidase C19 family. USP2 subfamily.
    • ドメインThe different N-terminus extensions of isoform 1 and isoform 4 determine their respective subcellular localization and differentiel effect on myoblast fusion and accumulation of muscle-specific proteins. The different N-terminus extensions of isoform 1 and isoform 4 are not essential for their catalytic activity.
    • 細胞内局在Nucleus and Cytoplasm. Cytoplasm > perinuclear region. Localizes in the spermatid head in late-elongating spermatids in the thin area between the outer acrosomal membrane and the plasma membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 41 kDa ubiquitin specific protease antibody
      • 41 kDa ubiquitin-specific protease antibody
      • Deubiquitinating enzyme 2 antibody
      • Ubiquitin carboxyl terminal hydrolase 2 antibody
      • Ubiquitin carboxyl-terminal hydrolase 2 antibody
      • ubiquitin specific peptidase 2 antibody
      • Ubiquitin specific processing protease 2 antibody
      • Ubiquitin specific protease 12 antibody
      • Ubiquitin specific protease 9 antibody
      • Ubiquitin specific protease, 41kD antibody
      • Ubiquitin thioesterase 2 antibody
      • Ubiquitin thiolesterase 2 antibody
      • Ubiquitin-specific-processing protease 2 antibody
      • Ubiquitin-specific-processing protease testis antibody
      • UBP-t antibody
      • UBP2_HUMAN antibody
      • UBP41 antibody
      • USP2 antibody
      • USP9 antibody
      see all

    Anti-USP2 antibody - Aminoterminal end 画像

    • Anti-USP2 antibody - Aminoterminal end (ab71796) at 1/100 dilution + HL60 cell lysate at 12.5 µg

      Predicted band size : 68 kDa
      Observed band size : 68 kDa

    Anti-USP2 antibody - Aminoterminal end (ab71796) 使用論文

    ab71796 has not yet been referenced specifically in any publications.

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    ab71796, Anti-USP2 antibody - Aminoterminal end antibody detect the N-terminal of USP2. It detects USP2 isoform a (USP2a) only but not USP2b.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"